latest version: 2013.1

CellNetAnalyzer Model Repository

This page serves as a repository for CellNetAnalyzer models. In the two tables below, models of mass- and signal-flow networks are listed. If you have a model that should be included in this repository please prepare the information for the new table entry and contact us.

Download and installation instructions

You can download a zip-file containing the CellNetAnalyzer project by clicking on the model name. Unzip the file at an appropriate location, at best as a sub-directory of CellNetAnalyzer's main directory. After unzipping, load MATLAB and CellNetAnalyzer. You can register the model by clicking on 'New' in the project manager, inserting the name of the project and the name of the project directory and then clicking on 'Save'. You are then asked whether the file 'app_para.m' in the network directory should be overwritten. After clicking on 'No' the model is visible as last entry in the project manager. Note: sometimes (if the creator of the network used absolute path specifications) you need to adapt the path specifications given in 'app_para.m'.

Mass-flow (metabolic) networks

Model Authors Description References Year
E. coli Joerg Stelling et al. E.coli central metabolism PubMed 2002
Purple nonsulfur bacteria Hädicke et al. Purple nonsulfur bacteria - central metabolism open acess 2011

Signal-flow (signal transduction) networks

Model Authors Description References Year
T-cell Julio Saez-Rodriguez et al. Large-scale logical model of primary T-cells open access 2007
Glucose Repression Tobias Sidelmann Christensen et al. Logical model of yeast glucose repression open access 2009
H. pylori and HGF Raimo Franke et al. Logical model of hepatocyte growth factor (HGF) and H. pylori induced c-Met signal transduction open access 2009
EGFR/ErbB Regina Samaga et al. Large-scale logical model of EGFR/ErbB signaling in hepatocytes open access 2009
Apoptosis Rebekka Schlatter et al. Logical model of apoptosis (based on data from mouse, rat and man) open access 2009
IL-1 signaling Ryll et al. Logical model of IL-1 signaling PubMed 2011
IL-6 signaling Ryll et al. Logical model of IL-6 signaling PubMed 2011
G1/S cell cyle regulation Huard et al. Logical model of G1/S cell cyle regulation integrating diverse signaling pathways (validated for hepatocytes) open access 2012
HGF interaction graph D'Allessandro et al. Interaction graph model of HGF signaling in hepatocytes including well-established and candidate mechanisms (submitted) 2014
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